Virology (HCV)
"Genotype Determination of Hepatitis C Virus from Northern India: Identification of a new Subtype."
Published in Hepatitis Weekly, March 18th, 1996
According to the authors' abstract of an article published in Journal of Medical Virology, "Hepatitis C virus (HCV) shows substantial nucleotide sequence diversity distributed throughout the viral genome, with many variants showing only 68-79% overall sequence homology. This has led to problems in diagnosis of HCV using commercial immunoassays. Based on clustering of homologous sequences, various genotypes and subtypes of HCV have been described from different geographical regions. In the present study, 11 isolates from India were genotyped using sequence comparison for part of the nonstructural (NS5) and structural (core) regions. Parts of the genome covering 451 bp (nt 9-459) of the...
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Source: Hepatitis Weekly (1996-03-18)
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