"Standard Panel for Determination of HBV-DNA by Polymerase Chain Reaction."

According to an abstract submitted by the authors to the Falk Symposium Molecular Diagnosis and Gene Therapy, held October 22-23, 1995, in Basel, Switzerland, "Presence of Hepatitis B virus (HBV) in serum of chronic carriers appears to be the most accurate marker of viral replication and has been employed to disease course in patients receiving anti-viral therapy. A quantitative test for HBV-DNA presence in serum is in this aspect a valuable determinant to the other serological markers of HBV infection. In the clinical diagnosis, hybridization was usually used, however, the final clearance of HBV must be determined by a sensitive polymerase chain reaction (PCR). Determination of the...

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