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HBV Vaccines

"Antibody Level after Hepatitis B Vaccination in Hemodialysis Patients: Influence of Hepatitis C Virus Infection."

Published in Hepatitis Weekly, April 1st, 1996

According to the authors' abstract of an article published in American Journal of Nephrology, "Seroconversion after hepatitis B vaccine has been estimated to occur when the level of anti-HBs is higher than 10 IU/l, but recently is has been considered that an antibody titer above 100 IU/l is necessary to guarantee an efficacious protection. We prospectively studied the evolution of anti-HBs after primary vaccination (3 doses; Engerix B, 40 (mu)g each) in 56 seronegative and not previously vaccinated hemodialysis patients. Three months after vaccine administration, seroconversion (anti-HBs >10 IU/l) was found in 43 patients (76.7%), but an adequate response (titer > 100 IU/l) was...

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