Therapy (HBV)

INF-(alpha) Improved Anti-HBe Conversion in Children with HBV

Published in Hepatitis Weekly, May 6th, 1996

Treatment with interferon-alpha improved the seroconversion rate of antibody to hepatitis B e antigen (anti-HBe) with or without steroid pretreatment in children with chronic hepatitis B treated in an Italian study.

Although the efficacy of interferon treatment has been well documented in adults with chronic hepatitis B disease, the results in children are less conclusive because most clinical trials have included a small number of patients. In addition, the interpretation of the data is complicated by variations in interferon dose schedules, disparities in patient characteristics in terms of disease activity, or mode of infection and differences in rates of...

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Source: Hepatitis Weekly (1996-05-06)

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