"Cellular Proteins That Bind to the Hepatitis B Virus Posttranscriptional Regulatory Element."

According to the authors' abstract of an article published in Virology, "The hepatitis B virus posttranscriptional regulatory element (PRE), which resides in the 3' region of the viral S transcripts, is important for the high-level expression of these mRNA species. We have previously shown that the PRE acts intranuclearly in cis to allow efficient export of intronless transcripts into the cytoplasm, in a manner that is independent of viral transacting factors. We here present data demonstrating that there are widely dispersed subelements in the PRE that are important for its function. All of these subelements bind, albeit with different affinities, to the same or similar host nuclear...

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