Virology (Woodchuck Hepatitis Virus)

Virus Responsible for Distinct Tumor Behavior in WHV

Published in Hepatitis Weekly, June 24th, 1996

Viral determinants appear to be responsible for the distinct behaviors of woodchuck hepatitis virus (WHV) and ground squirrel hepatitis virus (GSHV) with regard to liver tumor induction, according to a report from Paris, France's Institut Pasteur.

Three hepatitis B viruses infecting humans, woodchucks, and ground squirrels increase the risk of hepatocellular carcinoma in their respective hosts. The woodchuck hepatitis virus, unlike the two other viruses, induces a rapid carcinogenic process characterized by viral DNA. The highly preferred target of insertional mutagenesis in woodchucks is N-myc2, an intronless N-myc gene.

In a...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Hepatitis Weekly

Source: Hepatitis Weekly (1996-06-24)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry