Therapy (HCV)

IFN Response Related to Its Effect on Liver Cells

Published in Hepatitis Weekly, July 29th, 1996

The response to interferon treatment in patients with chronic hepatitis C is directly related to the agent's effect on liver cells, according to a report from Sweden.

Hepatitis C virus (HCV) infection becomes chronic in the majority of patients, and serious long-term consequences such as liver cirrhosis and hepatocellular carcinoma are eventually seen in some of these patients.

Interferon alpha (IFN-(alpha)) treatment induces a biochemical response in approximately 50 percent of patients with chronic HCV, which is sustained after discontinuation of IFN treatment in half of the responders, usually accompanied by disappearance of HCV RNA from...

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Source: Hepatitis Weekly (1996-07-29)

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