Virology (HCV)

Three New Epitopes Within HCV Nucleotide Identified

Published in Hepatitis Weekly, July 29th, 1996

Researchers from Japan have identified three new epitopes within the hepatitis C virus nucleoprotein recognized by cytotoxic T cell epitopes.

Cytotoxic T lymphocytes (CTLs) are believed to be a major host defense against viral infection and have also been implicated in the immunopathogenesis of viral infection. HCV specific CTLs are present in both the peripheral blood and among lymphocytes (PBLs) or lymphocytes infiltrating the liver of patients with HCV infection have been identified in association with HLA B44, B35, A29, B50, A11, B7, B51, B53, A23, A3, B8 and A2.

In this study researcher Takashi Kaneko and colleagues describe new epitopes within...

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Source: Hepatitis Weekly (1996-07-29)

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