Published in Hepatitis Weekly, August 5th, 1996
Cryoglobulinemia is a condition characterized by the presence of serum proteins which reversibly precipitate in the cold. They have been classified into three types: type I, single monoclonal immunoglobulin; type II, monoclonal immunoglobulin associated with a polyclonal component; type III, polyclonal immunoglobulin. Cryoglobulinemia may be idiopathic: essential mixed cryoglobulinemia corresponding to types II or III, or secondary to various diseases.
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