Hepatocellular Carcinoma (HBV)
"Detection of Hepatitis B Virus Genome in Hepatocellular Carcinoma from Both Hepatitis B Surface Antigen- and Antibody to Hepatitis C Virus-Negative Patients: A Study Using Polymerase Chain Reaction."
Published in Hepatitis Weekly, August 5th, 1996
According to the authors' abstract of an article published in Oncology Reports, "Twenty-two patients who tested seronegative for both hepatitis B virus (HBV) and hepatitis C virus (HCV) markers and undefined pathogenesis of hepatocellular carcinoma (HCC) were studied using polymerase chain reaction (PCR). Among these patients, 5 (23%) were positive for HBV-DNA in serum by PCR, but no patient was positive for HCV-RNA by reverse transcription PCR. Liver tissue specimens were available for analyzing HBV genome by PCR in 17 patients, and HBV sequences were detected in 10 (59%) patients. These results indicate that HBV is commonly implicated in serologically undefined pathogenesis of HCC in...
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Source: Hepatitis Weekly (1996-08-05)
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