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Therapy (HCV)

"Alpha But Not Beta Interferon Is Useful in Chronic Active Hepatitis Due to Hepatitis C Virus - A Prospective, Double-Blind, Randomized Study."

Published in Hepatitis Weekly, August 5th, 1996

According to the authors' abstract of an article published in Digestive Diseases and Sciences, "Interferon-alpha has been widely used in chronic hepatitis C, but controlled studies with intramuscular interferon-beta are lacking. We therefore performed a prospective, double-blind, randomized study comparing intramuscular IFN-alpha and -beta in patients with chronic hepatitis C. Sixty patients were randomly assigned to receive 3 MU thrice weekly intramuscularly of either recombinant IFN-alpha or leukocyte IFN-alpha or fibroblast IFN-beta for six months. Nine of 20 patients (45.0%) in the recombinant IFN, 5/19 (26.3%) in the leukocyte IFN, and none in the IFN-beta group had a complete...

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