Published in Hepatitis Weekly, August 12th, 1996
Cross-sectional studies have found that hepatitis B core gene mutations are associated with active liver disease and responsiveness to interferon therapy. In view of the heterogeneity in published sequences, it is not possible to tell whether the differences in sequences observed were true mutations that developed during the course of infection.
In this longitudinal study researcher Hakan Bozkaya and colleagues sought to determine the rate of hepatitis B core gene...
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