Therapy (HCV)

IFN-(alpha) Treatment Diminishes Th2 Response in HCV Disease

Published in Hepatitis Weekly, August 19th, 1996

An activated T-cell response is present in patients with hepatitis C-related liver disease and treatment with interferon alpha diminishes the T-helper type 2 response, according to a report from San Francisco's California Pacific Medical Center.

Interferon alpha (IFN-(alpha)) has been shown to be effective in some patients with hepatitis C virus (HCV) disease. Although it is known that IFN-(alpha) can reduce HCV RNA levels, the exact manner of immunoregulation is not known.

"T lymphocytes and immunoregulatory cytokines may be important in the host response to HCV infection," researcher Thomas V. Cacciarelli and colleagues wrote ("Immunoregulatory...

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Source: Hepatitis Weekly (1996-08-19)

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