Therapy (HCV)

Interferon Induced ANAs Don't Affect Treatment

Published in Hepatitis Weekly, August 26th, 1996

The administration of interferon to patients with chronic hepatitis C virus frequently produces antinuclear antibody, but this does not appear to affect treatment efficacy, according to a report from Japan.

An autoimmune mechanism has been reported to be involved in the pathogenesis of type-C viral hepatitis. It has been suggested that hepatitis C virus (HCV) may affect the immunologic functions of hosts during long persistent infection and may induce aberrant tissue autoantibodies, similar to those seen in autoimmune hepatitis (AIH). In contrast to AIH patients, the autoantibodies found in viral hepatitis patients are usually of low titers.

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Source: Hepatitis Weekly (1996-08-26)

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