Virology

Duck Hepatitis B Acts as Core Protein Translation Suppressor

Published in Hepatitis Weekly, September 16th, 1996

A report from Edmonton, Canada's University of Alberta adds to the understanding of the mechanism of the hepadnaviral nucleocapsid assembly.

The hepadnaviruses are a family of small, enveloped, hepatotropic DNA viruses, including hepatitis B virus of humans, woodchucks (WHV), ducks (DHBV), groundsquirrels and herons. All hepadnaviruses have similar genomic sizes (approximately 3.0 to 3.2 kb), morphological structures, and replication strategies.

Viral DNA replication takes place in a replicating core which consists of an RNA template, a viral polymerase, and core protein molecules. Encapsidation of the RNA template is under stringent regulatory...

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Source: Hepatitis Weekly (1996-09-16)

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