Published in Hepatitis Weekly, September 16th, 1996
The hepadnaviruses are a family of small, enveloped, hepatotropic DNA viruses, including hepatitis B virus of humans, woodchucks (WHV), ducks (DHBV), groundsquirrels and herons. All hepadnaviruses have similar genomic sizes (approximately 3.0 to 3.2 kb), morphological structures, and replication strategies.
Viral DNA replication takes place in a replicating core which consists of an RNA template, a viral polymerase, and core protein molecules. Encapsidation of the RNA template is under stringent regulatory...
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