Virology (HBV)

Natural Hepatitis B Variants Associated with Viremia

Published in Hepatitis Weekly, September 16th, 1996

Naturally occurring hepatitis B variants, found in patients with long-standing viral replication and active hepatic inflammation, are associated with significantly lower levels of viremia, according to researchers from the United Kingdom.

George Marinos and colleagues further noted that these variants always coexist with the wild-type hepatitis B virus (HBV), and that the presence of core gene deletion variants does not confer resistance to interferon-alpha (IFN-(alpha)) treatment.

Nucleotide sequence analysis of the HBV genome has shown considerable variation and heterogeneity in the virus population among different patients with chronic HBV...

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Source: Hepatitis Weekly (1996-09-16)

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