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Giant Cell Hepatitis

"Giant Cell Hepatitis with Auto-Immune Hemolytic Anemia: Effect of Splenectomy."

Published in Hepatitis Weekly, September 30th, 1996

According to the authors' abstract of an article published in Archives de Pediatrie, "Background: The previously reported cases of giant cell hepatitis with autoimmune hemolytic anemia were improved by prednisone plus azathioprine. Case report: A 14-month-old boy suffered from giant cell hepatitis with auto-immune hemolytic anemia and positive direct Coombs test. Prednisone and azathioprine administration improved the liver disease but failed to control hemolysis so that repeated blood transfusions were necessary. Persistance of severe degree of hemolysis required splenectomy that was promptly and definitively effective. Azathioprine and prednisone were pursued for a...

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