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Therapy (HCV)

"Pseudouridine for Monitoring Interferon Treatment of Patients with Chronic Hepatitis C."

Published in Hepatitis Weekly, October 28th, 1996

According to the authors' abstract of an article published in European Journal of Clinical Chemistry and Clinical Biochemistry, "Pseudouridine is a modified nucleoside derived from RNA catabolism; the concentration of this nucleoside is elevated in body fluids of both tumour-bearing and human immunodeficiency virus (HIV) infected patients. We used an HPLC procedure to evaluate the serum pseudouridine concentration in patients with chronic hepatitis C in an attempt to determine whether the nucleoside serum concentration was related to the response to a-interferon treatment. We found that: a) pseudouridine serum concentration was increased significantly in 76% (29/39) of patients with...

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