Virology (HBV)
Specific Precore Mutations Linked to Liver Damage
Published in Hepatitis Weekly, November 4th, 1996
According to researcher Magnus Lindh and colleagues, these findings indicate that such mutations represent a viral escape that reduces the host's immune response and, consequently, the necroinflammatory activity.
After its discovery in 1972, the hepatitis B e antigen (HBeAg) was found to be a useful marker of infectivity and liver damage. Seroconversion of the HBeAg antibody was shown to indicate a reduction in viral replication and clinical improvement. It later...
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Source: Hepatitis Weekly (1996-11-04)
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