Plasmodium falciparum (Therapy-Arteflene)
"Arteflene Compared with Mefloquine for Treating Plasmodium falciparum Malaria in Children."
Published in Hepatitis Weekly, November 11th, 1996
According to the authors' abstract of an article published in American Journal of Tropical Medicine and Hygiene, "Arteflene is a synthetic peroxide recently developed from an indication of antimalarial activity found in the Chinese plant Artabotrys uncinatus. The new antimalarial was compared against mefloquine in a Phase 3, open-labeled, randomized trial in children with uncomplicated Plasmodium falciparum malaria in Gabon. Patients received single oral doses of either 25 mg/kg of arteflene suspension or 15 mg/kg of mefloquine tablets. High-grade (RII and RIII) resistance was observed in eight (40%) of the 20 patients receiving the single dose of arteflene, but in none of...
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Source: Hepatitis Weekly (1996-11-11)
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