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HGV/HCV Coinfection

"Histopathologic Impact of GB Virus C Infection on Chronic Hepatitis C."

Published in Hepatitis Weekly, February 17th, 1997

According to the authors' abstract of an article published in Gastroenterology, "Background & Aims: Dual infection by hepatitis GB virus type C (GBV-C) and hepatitis C virus (HCV) is common. To assess the histopathologic impact of GBV-C infection on lister lesions, liver biopsy specimens of 105 patients chronically infected with HCV, 17 of whom (15%) were also infected with GBV-C, were reviewed. Methods: Semiquantitative histopathologic assessment of liver lesions was performed using the Knodell's score and the METAVIR grading system. Results: Hepatitis activity was mild, moderate, or severe in 3 (18%), 11, (64%), and 3 (18%) patients, respectively, infected...

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