Disease Markers

LKM-3 Rare Marker of Autoimmune Hepatitis

Published in Hepatitis Weekly, February 24th, 1997

Liver-kidney microsomal antibody type 3 appears to be a rare marker of autoimmune hepatitis, according to a German study.

Researcher Christian P. Strassburg and colleagues described a molecular target and titer difference between liver-kidney microsomal antibodies type 3 (LKM-3) autoantibodies in German subjects with hepatitis D virus and autoimmune hepatitis.

"In viral hepatitis, LKM-3/anti uridine 5'-diphosphate-glucuronosyltransferases (UGT-1) autoantibodies were exclusively observed in six percent of German patients diagnosed with chronic hepatitis D virus (HDV) infection," Strassburg et al. wrote ("Autoantibodies Against Glucuronosyltransferases...

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Source: Hepatitis Weekly (1997-02-24)

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