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Therapy (Hepatitis)

"A Practical Guide to the Use of Interferons in the Management of Hepatitis Virus Infections."

Published in Hepatitis Weekly, March 3rd, 1997

According to the authors' abstract of an article published in Drugs, "The recommended interferon dosage for patients with chronic hepatitis and typical hepatitis B virus (HBV) infection is 10MU 3 times weekly for 4 to 6 months; with such a regimen sustained alanine aminotransferase (ALT) normalization, liver histology improvement, clearance of HBV DNA and seroconversion from hepatitis B e antigen (HBeAg) to anti-HBe are obtained in about 40% of treated patients. Patients with elevated disease activity (high ALT values, active chronic hepatitis, low HBV DNA levels) tend to respond better to therapy; Oriental patients and immunocompromised patients are not ideal candidates for interferon. ...

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