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Transplantation (HCV)

"Hepatitis C Virus-Related Fibrosing Cholestatic Hepatitis after Renal Transplantation."

Published in Hepatitis Weekly, March 3rd, 1997

According to the authors' abstract of an article published in Transplantation, "Fibrosing cholestatic hepatitis is a well-described syndrome in patients with immunodeficiency and chronic hepatitis B. It is clinically, biologically, and histologically characterized by rapidly progressive hepatic failure, a mildly elevated serum aminotransferase level, an extensive periportal fibrosis associated with intense cholestasis, mild inflammatory cellular infiltrate, no cirrhosis, and a high hepatocellular level expression of B viral antigens. This syndrome reflected a direct hepatocytopathic injury linked to high intrahepatic viral antigen expression. Because the syndrome of fibrosing...

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