Diagnostics (HCV)

Current Assays Don't Detect Mixed Infections in Hemophiliacs

Published in Hepatitis Weekly, March 24th, 1997

Current diagnostic assays are not suitable for a true appraisal of mixed hepatitis C virus infection in hemophiliacs, according to a French study.

Hepatitis C virus (HCV) is currently the most common cause of post-transfusion and sporadic non-A/non-B hepatitis (NANBH). The introduction of clotting factor concentrates in the 1970s was largely responsible for the transmission of HCV in hemophiliacs. It has been estimated that between 49 and 100 percent of hemophiliacs who received non-virus-inactivated concentrates show evidence of HCV antibodies.

"In French hemophiliacs who have been transfused repeatedly, anti-HCV antibodies are detected in 69.6...

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Source: Hepatitis Weekly (1997-03-24)

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