"Booster Immunization of Low- and Non-Responders after a Standard Three Dose Hepatitis B Vaccine Schedule - Results of a Post-Marketing Surveillance."

According to the authors' abstract of an article published in Vaccine, "Seventy-nine low-responders and 83 non-responders after a previous three-dose hepatitis B (HE) vaccine course at 0, 1, and 6 months were enrolled to receive additional 20 (mu)g recombinant HE vaccine doses every 2 months until all had anti-HBs levels greater than or equal to 100 mIU ml(-1). After the first booster, 65.4% had anti-HBs levels greater than or equal to 100 mIU ml(-1), 17.9% were low-responders (10-99 mIU ml(-1)), and 16.7% remained non-responders (<10 mIU ml(-1)). All complying non-responders developed anti-HBs levels greater than or equal to 100 mIU ml(-1) after the third booster at the latest,...

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