Epidemiology (HBV)

Hepatitis B Mutant Described in Heart Transplant Patient

Published in Hepatitis Weekly, June 30th, 1997

A hepatitis B virus mutant with a new hepatocyte nuclear factor 1 binding site was identified in a heart transplant recipient who died of fulminant hepatitis B transmitted by the donor.

"Our results clearly show that a novel viral population different from that present in the infectious source rapidly emerged and accumulated in the transplant recipient during fulminant hepatitis," researcher Irmgard Pult and colleagues wrote ("A Hepatitis B Virus Mutant with a New Hepatocyte Nuclear Factor 1 Binding Sites Emerging in Transplant-Transmitted Fulminant Hepatitis B," Hepatology, June 1997;25(6):1507-1515).

Organ-transmitted hepatitis B virus (HBV)...

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Source: Hepatitis Weekly (1997-06-30)

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