Published in Hepatitis Weekly, August 11th, 1997
An etiological role for hepatitis C virus (HCV) in the pathogenesis of mixed cryoglobulinemia has been suggested due to the demonstration of enriched HCV RNA in serum cryoprecipitates (Agnello et al., N Engl J Med 1992;327:1490-1495). In addition, cryoglobulinemia was observed in HCV infected patients within a few months after liver transplantation when recurrent disease of the liver allograft was histologically mild (Gournay et al., Gastroenterology 1996;110:265-267).
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