Therapy (HCV)

Larger Doses of IFN Needed in Those with Genotype 1

Published in Hepatitis Weekly, August 18th, 1997

Larger than normal doses of interferon alpha may be needed to treat hepatitis C virus patients with genotype 1, according to a multicenter report.

In those with hepatitis C virus (HCV) disease, several pretreatment factors are predictive of response to interferon (IFN) including baseline serum HCV RNA levels and HCV genotype. Recent studies showed that patients with HCV genotype 1a or 1b respond less favorably to IFN-(alpha) treatment (3 mIU tiw), with sustained response rates of less than 10 percent to 20 percent (Mahaney et al., Hepatology 1994;20:1405-1411; Yoshioka et al., Hepatology 1992;16:293-299).

"It is unknown whether a different dosing...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Hepatitis Weekly

Source: Hepatitis Weekly (1997-08-18)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry