Immunology (HCV)
"Immunodominant CD4+ T-Cell Epitope Within Nonstructural Protein 3 in Acute Hepatitis C Virus Infection."
Published in Hepatitis Weekly, September 15th, 1997
According to the authors' abstract of an article published in Journal of Virology, "In acute hepatitis C virus infection, 50 to 70% of patients develop chronic disease. Considering the low rate of spontaneous viral clearance during chronic hepatitis C infection, the first few months of interaction between the patient's immune system and the viral population seem to be crucial in determining the outcome of infection. We previously reported the association between a strong and sustained CD4+ T-cell response to nonstructural protein 3 (NS3) of the hepatitis C virus and a self-limited course of acute hepatitis C infection. In this study, we identify an immunodominant...
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Source: Hepatitis Weekly (1997-09-15)
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