"Hepatitis C Virus Replication Systems Using Two Cultured Cell Lines."

According to an abstract submitted by the authors to the 4th International Meeting on Hepatitis C Virus and Related Viruses, Molecular Virology and Pathogenesis, held March 6-10, 1997, in Kyoto, Japan, "We recently developed hepatitis C virus (HCV) replication systems by using two cultured human cell lines: MT-2, a human T-cell leukemia virus type 1-infected cell line, and PH5CH, a non-neoplastic human hepatocyte line. Furthermore, we obtained cloned MT-2C and PH5CH1 cells, which are more susceptible than the original MT-2 and PH5CH cells, respectively, to HCV infection and can support HCV replication over 30 days post-inoculation (p.i.). We obtained several evidences regarding HCV...

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