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Therapy (HCV)

"Kinetics of HCV Viremia in Kidney Transplant Recipients During and After Alpha-Interferon Therapy."

Published in Hepatitis Weekly, November 17th, 1997

According to the authors' abstract of an article published in American Journal of Nephrology, "Fifteen kidney transplant recipients with chronic hepatitis C were given 3 million units recombinant alpha(2b)-interferon for 142 ± 35 days. There were significant decreases in hepatitis C virus (HCV) RNA 1 month after the initiation of treatment (p<0.01), and at the end of treatment (p<0.05). HCV RNA was undetectable by PCR analysis during treatment in 5 patients. But HCV RNA reappeared in all patients 1 month after the cessation of therapy, and the level of viremia returned to baseline. While all patients had normalized alanine aminotransferase (ALT) activities at...

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