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Transmission (GBV-C)

"Mother-to-Infant Transmission Occurs More Frequently with GB Virus C Than Hepatitis C Virus."

Published in Hepatitis Weekly, March 23rd, 1998

According to the authors' abstract of an article published in Archives of Virology, "A total of 107 hepatitis C virus (HCV)-infected pregnant women were screened for GB virus C (GBV-C) RNA in their sera, and 11 (10.3%) were positive. Among 11 infants born to these HCV/GBV-C co-infected mothers, GBV-C RNA was detected in 7 (63.6%) while HCV RNA was found in 1 (9.1%) within 1 year after birth: this difference was statistically significant (p=0.023). The mothers of infected infants had significantly higher serum titers of GBV-C RNA than those of uninfected infants: 10(6.7 ± 0.5) vs. 10(4.0 ± 1.0) copies/ml in average (p=0.001). The baby in whom HCV RNA was...

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