HCV/HIV Coinfection

"Impact of Treatment with Human Immunodeficiency Virus (HIV) Protease Inhibitors on Hepatitis C Viremia in Patients Coinfected with HIV."

Published in Hepatitis Weekly, April 6th, 1998

According to the authors' abstract of an article published in Journal of Infectious Diseases, "The impact of human immunodeficiency virus (HIV) protease inhibitors on hepatitis C (HCV) viremia was assessed in 19 patients infected with both HIV and HCV. HIV and HCV RNA levels were measured before and during treatment with protease inhibitors. Before treatment, mean levels of HCV RNA were 5.3 log for HCV RNA and 5.0 log for HIV RNA. CD4 lymphocyte counts were 63/mm³. After 6 weeks of treatment, a mean reduction of 2.1 log(10) in HIV RNA (P<.001) and a mean (±SE) increase of 73 (±21) CD4 and 296 (±70) CD8 cells were observed (P<.05). In...

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Source: Hepatitis Weekly (1998-04-06)

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