Transmission (HBV)

Neonatal HBV Strain is Generally Identical to Mothers'

Published in Hepatitis Weekly, May 11th, 1998

Mother-to-infant transmission of fulminant hepatitis B may not be influenced by the virulence or mutagenicity of the mother's infection, according to a report from Germany.

The case report found that emergence of neonatal fulminant hepatitis B appears to result from de novo infection of the child with the same hepatitis B e antigen (HBeAg) and pre-S2-defective hepatitis B virus population as seen in the mother.

Researcher Martina Sterneck and colleagues found that neither the emergence of a particular mutant strain nor infection with highly replicating hepatitis B variants are necessary for the development of neonatal fulminant hepatitis B virus...

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Source: Hepatitis Weekly (1998-05-11)

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