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Antiviral Therapy (HBV)

Disabling Formation of Viral Envelope May Help Reduce HBV, HCV Infection

Published in Hepatitis Weekly, May 11th, 1998

A new way to fight the hepatitis B and C viruses may be on the horizon.

Timothy Block, PhD, of the Jefferson Medical College, Thomas Jefferson University in Philadelphia, Pennsylvania, and his colleagues at several institutions have found that by interfering with a specific step in the life cycle of the woodchuck hepatitis virus, the virus can't reproduce, shutting down its ability to infect a cell.

By blocking the creation of a virus "envelope", the viral DNA is locked within the infected cell. As a result, levels of the virus in the animals' bloodstream drop dramatically. The researchers said that the work may provide leads to improved methods of...

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