Liver Transplantation (HBV)

Pre-Transplant Markers Do Not Predict Later Immunoprophylaxis Requirements

Published in Hepatitis Weekly, July 13th, 1998

Results of an attempt to correlate pre-transplant markers for hepatitis B virus (HBV) with post-transplant immunoprophylaxis requirements in infected patients with end-stage liver disease suggest that another approach to this goal may be warranted.

University of Virginia researchers, reporting in the Annals of Surgery, found measuring levels of pre-transplant markers "was an overall poor predictor of HBIg [hepatitis B immunoglobulin] requirements after the transplant" (Sawyer et al., "Improved Clinical Outcomes with Liver Transplantation for Hepatitis B-Induced Chronic Liver Failure Using Passive Immunization," Ann Surg, June 1998;227(6):841-850).

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Source: Hepatitis Weekly (1998-07-13)

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