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HGV/HIV Coinfection

"GB Virus C/Hepatitis G Virus Infection: A Favorable Prognostic Factor in Human Immunodeficiency Virus Infected Patients?."

Published in Hepatitis Weekly, July 27th, 1998

According to the authors' abstract of an article published in Journal of Infectious Diseases, "To investigate a possible influence of GB virus C (GBV-C) in immunocompromised patients, the prevalences of GBV-C RNA and anti-E2 antibody in 197 human immunodeficiency virus (HIV) infected patients and in 120 control blood donors were studied. GBV-C RNA was detected in 33 of 197 HIV infected patients (16.8%) compared with 1 in 120 blood donors (0.8%) (P<.001). Previous exposure to GBV-C (anti-E2 antibody-positive) was shown in 56.8% of HIV patients and in 9% of blood donors. GBV-C viremia was not associated with hepatitis. Despite approximately equal duration of HIV infection in...

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