Published in Hepatitis Weekly, October 5th, 1998
The quasispecies nature of hepatitis C virus (HCV) and the antigenic drift of this virus have been proposed as mechanisms for viral persistence. Chronic HCV infection occurs in the presence of circulating antibodies against structural and nonstructural proteins, indicating that humoral immunity is not protective in this infection, possibly because of emergence of scape strains within the quasispecies of the...
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