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Viral Replication (HCV)

HCV Shown to be Lymphotropic in HIV+ Patients

Published in Hepatitis Weekly, October 19th, 1998

Hepatitis C virus can and does replicate outside the liver, at least in immunocompromised patients such as those with HIV infection.

Researchers from Pennsylvania's University of Pittsburgh found that hepatitis C virus (HCV) was lymphotropic in a group of HIV infected patients.

"We demonstrated for the first time the presence of active HCV replication in peripheral blood mononuclear cells and lymph nodes in patients infected with HIV," Tomasz Laskus and colleagues wrote ("The Presence of Active Hepatitis C Virus Replication in Lymphoid Tissue in Patients Coinfected with HIV 1," Journal of Infectious Diseases, October 1998;178:1189-1192).

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