Hepatic Iron Accumulation (HCV)
"The Relation of Iron Status and Hemochromatosis Gene Mutations in Patients With Chronic Hepatitis C."
Published in Hepatitis Weekly, February 8th, 1999
According to the authors' abstract of an article published in Gastroenterology, "Background & Aims: Elevated hepatic iron concentration may affect the response to antiviral therapy in chronic hepatitis C. This study explored the contribution of genetic hemochromatosis to iron accumulation in chronic hepatitis C. Methods: HFE mutations (C282Y and H63D) were assessed in 184 patients with chronic hepatitis C virus and 487 controls. Liver biopsy specimens were available in 149 patients. Hepatic iron content was measured in 114 patients by atom-absorption spectrophotometry. Results: The C282Y and H63D allele frequencies were 7.06 and 11.6 in patients and 4.83 and...
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Source: Hepatitis Weekly (1999-02-08)
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