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Therapy (HCV)

"Modeling the Impact of Interferon alfa Treatment on Liver Fibrosis Progression in Chronic Hepatitis C: A Dynamic View."

Published in Hepatitis Weekly, March 8th, 1999

According to the authors' abstract of an article published in Gastroenterology, "Background & Aims: Impact of hepatitis C treatment has never taken into account the dynamics of fibrosis progression. This study assessed the impact of interferon on liver fibrosis progression in patients with chronic hepatitis C according to 3-month aminotransferase activity response. Methods: We recruited 287 patients, 185 treated and 102 control, with paired biopsy specimens. Before follow-up, the fibrosis progression rate per year was estimated as the ratio between fibrosis stage in METAVIR units (1 U, 1 stage; 4 U, cirrhosis) and the duration of infection. During follow-up, fibrosis...

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