Therapy (HCV)

Liver Fibrosis Following IFN Examined

Published in Hepatitis Weekly, March 8th, 1999

Interferon's mechanism of action against liver fibrosis in patients with chronic hepatitis C virus was examined in a study from Japan.

The proliferation and differentiation of stellate (Ito, or fat-storing) cells into myofibroblast-like cells is responsible for the development of liver fibrosis.

Using computer image analysis, I. Sakaida and colleagues evaluated the changes of alpha smooth muscle actin-positive stellate cells and liver fibrosis after interferon-alpha or -beta (IFN-alpha, beta) therapy in patients with chronic hepatitis C ("Quantitative Analysis of Liver Fibrosis and Stellate Cell Changes in Patients with chronic Hepatitis C After...

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Source: Hepatitis Weekly (1999-03-08)

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