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Complicating Conditions

10 Percent of Patients with HCV-Renal Disease Require Dialysis

Published in Hepatitis Weekly, April 19th, 1999

Approximately one in ten patients with hepatitis C virus-associated renal disease eventually requires dialysis, a review from the U.S. Veteran's Administration suggests.

Hepatitis C is an important cause of renal disease, and renal complications may be the presenting manifestation of hepatitis C infection. About half of patients present with evidence of renal insufficiency, and up to one quarter present with nephrotic syndrome. Others present with proteinuria or evidence of diminished renal function.

"The pathogenesis of hepatitis C-associated renal disease remains incompletely defined, but most evidence suggests that glomerular injury results from...

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