"Close Association Between High Serum ALT and More Rapid Development and Higher Incidence of Hepatocellular Carcinoma in HCV-Associated Cirrhosis."

According to an abstract submitted by the authors to the 90th Annual Meeting of the American Association for Cancer Research, held April 10-14, 1999, in Philadelphia, Pennsylvania, "Whether or not persistent elevation of serum alanine aminotransferase (ALT) levels correlates with the development of hepatocellular carcinoma (HCC) was studied in patients with hepatitis C virus (HCV) associated liver cirrhosis (LC) of early stage. 69 consecutive patients with biopsy proven HCV-associated LC (Child's stage A) who had been followed up for more than five years for HCC development were studied. They were subdivided into three groups according to their serum ALT levels; (A) 32 patients whose...

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