Published in Hepatitis Weekly, May 10th, 1999
Almost all HIV positive hemophiliacs are also hepatitis C virus (HCV)-positive. HCV infection generally occurs immediately after the first exposure to unscreened factor concentrates. The major consequence of chronic HCV infection is progression to hepatic cirrhosis and its associated clinical complications, namely, ascites, jaundice, variceal bleeding and encephalopathy, and hepatocellular carcinoma (HCC).
In those not infected with HIV, HCV-related cirrhosis develops in 20 percent to 30 percent within two...
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