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Viral Persistence

Small Number of People Retain HEV Antibodies

Published in Hepatitis Weekly, May 17th, 1999

A very small percentage of people apparently retain hepatitis E virus antibody persistence for long periods of time, with older people showing more persistence than younger ones.

The prevalence of anti-HEV was assessed in 2,233 subjects aged 20-79 years in the Republic of San Marino in the years 1990-1991. The sera were tested by ELISA and further confirmed by Western blot (WB) analysis ("Seroprevalence and Anti-HEV Persistence in the General Population of the Republic of San Marino," Journal of Medical Virology, May 1999;58(1):49-53).

The overall anti-HEV prevalence was 1.5 percent. A significant trend by age was observed. Anti-HEV prevalence was...

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