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Anti-HCV Core IgM Predict Long-Term IFN Response

Published in Hepatitis Weekly, May 24th, 1999

Hepatitis C virus antibody core immunoglobulin M levels may be sensitive predictors of long-term interferon response in patients with chronic hepatitis C infection.

In this study, C. Vandelli and colleagues evaluated the efficacy of a 12-month course of recombinant interferon (alpha) (IFN-(alpha)2b) and assessed predictive factors of successful response to IFN therapy in chronic active hepatitis C (HCV CAH) ("Prediction of Successful Outcome in a Randomized Controlled Trial of the Long-Term Efficacy of Interferon (alpha) Treatment for Chronic Hepatitis C," Journal of Medical Virology, May 1999;58(1):26-34).

A total of 242 patients with histologically...

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