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Neurology

IFN-(alpha) Can Induce Mild Encephalopathy

Published in Hepatitis Weekly, August 9th, 1999

A blinded Japanese study examined the effect of alpha interferon therapy on the brain waves of patients being treated for chronic hepatitis C.

Researcher S. Kamei and colleagues from Tokyo's Nihon University School of Medicine estimated the effect of brain function due to interferon (IFN)-alpha in chronic hepatitis C patients by the quantitative EEG ("Blinded, Prospective, and Serial Evaluation by Quantitative-EEG in Interferon-Alpha-Treated Hepatitis C," Acta Neurol Scand, July 1999;100(1):25-33).

Fifty-six chronic hepatitis C patients were administered IFN-alpha intramuscularly at 9x106 IU daily for the first four weeks and then three...

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