Blood Safety (HCV Contamination)

"High-Throughput Extraction, Amplification, and Detection (HEAD) of HCV-RNA in Individual Blood Donations."

Published in Hepatitis Weekly, August 16th, 1999

According to the authors' abstract of an article published in Journal of Clinical Virology, "Background: High-throughput nucleic acid amplification techniques (NATs) are required for the detection of viral genomes in individual blood donations and might be helpful in any virological laboratory. Objective: To develop and automate a method for the detection of hepatitis C virus RNA in individual blood donations, compatible with the time schedule of routine blood bank screening an product release. Study Design: The viral RNA was isolated with the use of target specific capture oligonucleotides and magnetic beads. This extraction method was combined with reverse...

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Source: Hepatitis Weekly (1999-08-16)

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